HUMAN SERUM MACROGLOBULINS AND DISSOCIATION UNITS
نویسندگان
چکیده
منابع مشابه
Macroglobulins of Rat Serum
A three-stage method for isolation of a, macroglobulin and a2 macroglobulin from the serum of normal and injured rats is described. The methods successively used, namely gel filtration, ultracentrifugation and chromnatography on DEAE-cellulose, were chosen to minimize loss of tryptic esterase-protecting activity. The two proteins differed slightly with respect to the following properties: mol.w...
متن کاملSerum -macroglobulins in renal disease and preeclampsia.
The serum levels of alpha(2)-macroglobulin and pregnancy-associated globulin (another alpha-macroglobulin) have been measured by means of a radial immunodiffusion technique in (1) renal disease with and without proteinuria, (2) in age- and sex-matched controls, (3) in preeclampsia with and without proteinuria, and (4) in normal pregnant controls. There are significant increases in alpha(2)-macr...
متن کاملIndividual Antigenic Specificity of Human Macroglobulins
The localization of individually specific antigenic determinants on the monoclonal gammaM Mö was studied in gel diffusion experiments with 19S gammaM Mö and its 7S subunit. Various types of such determinants were delineated. Some were demonstrable both on the intact macroglobulin molecule and on the subunit. The latter was often unable to precipitate with the corresponding antibody, but combine...
متن کاملChromatographic properties of gamma globulin: behavior of serum gamma macroglobulins.
The cellulose ion exchangers (1) have proved to be useful chromatographic media for the serum proteins. In the fractionation of normal human serum on the anion exchanger, diethylaminoethyl (DEAE) cellulose, application of buffer gradients of increasing concentration and decreasing pH results in the appearance of components in the effluent fluid in order of increasing electrophoretic mobility (2...
متن کاملMacroglobulins 1. STUDIES ON THE ISOLATION AND PHYSICAL PROPERTIES OF PATHOLOGICAL MACROGLOBULINS BY A. ALBERT*
Annison, E. F. & Morgan, W. T. J. (1952). Biochem. J. 50, 460. Caspary, E. A. (1954). Biochem. J. 57, 295. Gibbons, M. N. (1955). Analy8t, 80, 268. Gibbons, R. A., Morgan, W. T. J. & Gibbons, M. N. (1955). Biochem. J. 60, 428. Gottschalk, A. & Simmonds, D. H. (1960). Biochim. biophy8. Acta, 42, 141. Kabat, E. A. (1956). Blood Group Substance8. New York: Academic Press Inc. Kekwick, R. A. (1950)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1958
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)70470-5